SCHEMBL2664696

SCHEMBL2664696

O=C(N/N=C/c1ccc(CNCc2ccc(OC(F)(F)F)cc2)c2ccccc12)c1ccc(O)c(Cl)c1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2663760 0.91 GCGR (0.79) GCGR
SCHEMBL2663929 0.89 GCGR (0.68) GCGR
SCHEMBL2663919 0.89 GCGR (0.72) GCGR
SCHEMBL2663762 0.88 GCGR (0.76) GCGR
SCHEMBL2664506 0.87 GCGR (1.00) GCGR
SCHEMBL2663863 0.87 GCGR (1.00) GCGR
SCHEMBL2664393 0.87 GCGR (1.00) GCGR
SCHEMBL2664088 0.87 GCGR (0.71) GCGR
SCHEMBL9071599 0.86 GCGR (0.81) GCGR
SCHEMBL2663936 0.86 GCGR (0.68) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999001423-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 1999-01-14 WO disclosed