Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.85 |
| ▸ | BCL2 | P10415 | 19/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26647932 | 1.00 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL31450711 | 1.00 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL26647946 | 1.00 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL26647869 | 0.95 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL26648509 | 0.95 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL26648502 | 0.95 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL31450771 | 0.95 | BCL2L1 (0.85) | BCL2L1BCL2 | |
| SCHEMBL26648516 | 0.95 | BCL2L1 (0.84) | BCL2L1BCL2 | |
| SCHEMBL31450622 | 0.95 | BCL2L1 (0.84) | BCL2L1BCL2 | |
| SCHEMBL26648560 | 0.95 | BCL2L1 (0.84) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |