Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33530304 | 0.93 | BCL2 (0.81) | BCL2 | |
| SCHEMBL26647919 | 0.90 | BCL2 (0.83) | BCL2 | |
| SCHEMBL31450702 | 0.90 | BCL2 (0.83) | BCL2 | |
| SCHEMBL26648065 | 0.87 | BCL2 (0.85) | BCL2 | |
| SCHEMBL31450830 | 0.87 | BCL2 (0.85) | BCL2 | |
| SCHEMBL31450938 | 0.87 | BCL2 (0.84) | BCL2 | |
| SCHEMBL26648821 | 0.87 | BCL2 (0.84) | BCL2 | |
| SCHEMBL30314055 | 0.87 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1699870 | 0.87 | BCL2 (1.00) | BCL2 | |
| SCHEMBL31450967 | 0.86 | BCL2 (0.77) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |