Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.39 |
| ▸ | BCL2 | P10415 | 5/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26648837 | 0.89 | CNR1 (0.45) | CNR1CNR2BCL2L1BCL2MEN1 | |
| SCHEMBL31450929 | 0.87 | MAPT (0.43) | USP2BCL2L1BCL2MEN1KMT2A | |
| SCHEMBL26648069 | 0.86 | BID (0.42) | USP2CNR1CNR2ENPP2BCL2L1 | |
| SCHEMBL26648664 | 0.86 | USP2 (0.40) | USP2CNR1CNR2ENPP2BCL2L1 | |
| SCHEMBL26648275 | 0.86 | BCL2L1 (0.38) | CNR1CNR2BCL2L1BCL2CCR1 | |
| SCHEMBL554396 | 0.85 | BCL2L1 (0.46) | USP2ENPP2BCL2L1BCL2 | |
| SCHEMBL553748 | 0.85 | BCL2L1 (0.46) | USP2ENPP2BCL2L1BCL2 | |
| SCHEMBL31450836 | 0.85 | BCL2L1 (0.46) | USP2ENPP2BCL2L1BCL2 | |
| SCHEMBL31451040 | 0.85 | BCL2L1 (0.46) | USP2ENPP2BCL2L1BCL2 | |
| SCHEMBL553747 | 0.85 | BCL2L1 (0.46) | USP2ENPP2BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |