Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.49 |
| ▸ | BID | P55957 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | BCL2 | P10415 | 17/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26648555 | 1.00 | BCL2A1 (0.49) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL26648566 | 0.93 | BCL2 (0.50) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL26648571 | 0.93 | BCL2 (0.50) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL31450586 | 0.93 | BCL2 (0.50) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL31450888 | 0.93 | BCL2 (0.50) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL26647789 | 0.89 | BCL2A1 (0.51) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL26648052 | 0.89 | BCL2A1 (0.51) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL31450986 | 0.89 | BCL2A1 (0.51) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL31450479 | 0.86 | BCL2 (0.46) | BCL2A1BIDMCL1BCL2 | |
| SCHEMBL26648456 | 0.86 | BCL2 (0.46) | BCL2A1BIDMCL1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |