Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.59 |
| ▸ | GIPR | P48546 | 3/20 | 0.53 |
| ▸ | ADCY6 | O43306 | 6/20 | 0.53 |
| ▸ | ADCY3 | O60266 | 6/20 | 0.53 |
| ▸ | ADCY9 | O60503 | 6/20 | 0.53 |
| ▸ | ADCY5 | O95622 | 6/20 | 0.53 |
| ▸ | ADCY8 | P40145 | 6/20 | 0.53 |
| ▸ | ADCY7 | P51828 | 6/20 | 0.53 |
| ▸ | ADCY2 | Q08462 | 6/20 | 0.53 |
| ▸ | ADCY1 | Q08828 | 6/20 | 0.53 |
| ▸ | ADCY4 | Q8NFM4 | 6/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665102 | 0.91 | GCGR (0.63) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665095 | 0.90 | GCGR (0.61) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL9071458 | 0.90 | GCGR (0.59) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL2664983 | 0.90 | GCGR (0.59) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL9071460 | 0.90 | GCGR (0.61) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL2665028 | 0.90 | GCGR (0.59) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL9071401 | 0.89 | GCGR (0.51) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL2665182 | 0.89 | GCGR (0.69) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL9071514 | 0.88 | GCGR (0.61) | GCGRGIPRADCY6ADCY3ADCY9 | |
| SCHEMBL2664986 | 0.88 | GCGR (0.54) | GCGRGIPRADCY6ADCY3ADCY9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |