Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.45 |
| ▸ | ADCY6 | O43306 | 6/20 | 0.44 |
| ▸ | ADCY3 | O60266 | 6/20 | 0.44 |
| ▸ | ADCY9 | O60503 | 6/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 6/20 | 0.44 |
| ▸ | ADCY8 | P40145 | 6/20 | 0.44 |
| ▸ | ADCY7 | P51828 | 6/20 | 0.44 |
| ▸ | ADCY2 | Q08462 | 6/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 6/20 | 0.44 |
| ▸ | ADCY4 | Q8NFM4 | 6/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GIPR | P48546 | 3/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664969 | 0.89 | GCGR (0.48) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2650616 | 0.86 | GCGR (0.39) | GCGRGIPR | |
| SCHEMBL2665011 | 0.85 | GCGR (0.46) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2664971 | 0.84 | GCGR (0.47) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665009 | 0.84 | GCGR (0.43) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665168 | 0.83 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665247 | 0.83 | GCGR (0.49) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL9071452 | 0.83 | GCGR (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2650613 | 0.82 | GCGR (0.60) | GCGRGIPR | |
| SCHEMBL9071422 | 0.82 | GCGR (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |