Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.43 |
| ▸ | GIPR | P48546 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GCG | P01275 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660535 | 1.00 | GCGR (0.43) | GCGRGIPRCYP2D6GCGPPARD | |
| SCHEMBL2649365 | 0.91 | GCGR (0.46) | GCGRGIPRCYP2D6GCGPPARD | |
| SCHEMBL2653228 | 0.91 | GCGR (0.46) | GCGRGIPRCYP2D6GCGPPARD | |
| SCHEMBL2665061 | 0.88 | GCGR (0.55) | GCGRGIPRPPARDCHRM4GLP1R | |
| SCHEMBL2660786 | 0.88 | GCGR (0.46) | GCGRGIPRCYP2D6GCGPPARD | |
| SCHEMBL2659923 | 0.86 | GCGR (0.45) | GCGRGIPRGCG | |
| SCHEMBL2654228 | 0.85 | GCGR (0.40) | GCGRGIPRGCGGLP1R | |
| SCHEMBL2654573 | 0.85 | GCGR (0.49) | GCGR | |
| SCHEMBL2653731 | 0.85 | HAO1 (0.46) | GCGRCYP2D6PPARD | |
| SCHEMBL2647399 | 0.84 | PPARD (0.47) | GCGRGIPRGCGPPARDGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |