Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.51 |
| ▸ | ADCY6 | O43306 | 5/20 | 0.51 |
| ▸ | ADCY3 | O60266 | 5/20 | 0.51 |
| ▸ | ADCY9 | O60503 | 5/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.51 |
| ▸ | ADCY8 | P40145 | 5/20 | 0.51 |
| ▸ | ADCY7 | P51828 | 5/20 | 0.51 |
| ▸ | ADCY2 | Q08462 | 5/20 | 0.51 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.51 |
| ▸ | ADCY4 | Q8NFM4 | 5/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665188 | 0.93 | BCL2L1 (0.48) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665102 | 0.89 | GCGR (0.63) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665181 | 0.89 | GCGR (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2664991 | 0.89 | GCGR (0.46) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665100 | 0.85 | GCGR (0.49) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665095 | 0.84 | GCGR (0.61) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665238 | 0.83 | GCGR (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665166 | 0.83 | GCGR (0.48) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665104 | 0.83 | GCGR (0.60) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665003 | 0.83 | GCGR (0.62) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |