Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648118 | 1.00 | CYP2D6 (0.43) | CYP2D6USP5GCGRNPC1RAB9A | |
| SCHEMBL2648116 | 1.00 | CYP2D6 (0.43) | CYP2D6USP5GCGRNPC1RAB9A | |
| SCHEMBL2647340 | 0.95 | GCGR (0.45) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2664958 | 0.95 | GCGR (0.45) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2649608 | 0.95 | GCGR (0.45) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2647338 | 0.95 | GCGR (0.45) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2649603 | 0.95 | GCGR (0.45) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2665118 | 0.92 | SMN1; SMN2 (0.47) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2648055 | 0.92 | SMN1; SMN2 (0.47) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2648057 | 0.92 | SMN1; SMN2 (0.47) | CYP2D6GCGRNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |