SCHEMBL2665144 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	GCGR	P47871	12/20	0.51

▸	GIPR	P48546	12/20	0.51

▸	GLP1R	P43220	2/20	0.44

▸	PPARD	Q03181	1/20	0.42

▸	TACR1	P25103	1/20	0.41

▸	KDM1A	O60341	1/20	0.41

▸	SERPINE1	P05121	1/20	0.38

▸	APAF1	O14727	1/20	0.37

▸	BCL2L1	Q07817	2/20	0.37

▸	MCL1	Q07820	2/20	0.37

▸	HAO1	Q9UJM8	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6916484	0.88	GCGR (0.53)	GCGRGIPRGLP1RAPAF1BCL2L1
SCHEMBL6916489	0.88	GCGR (0.53)	GCGRGIPRGLP1RAPAF1BCL2L1
SCHEMBL2651641	0.87	PPARD (0.47)	GCGRGIPRGLP1RPPARDKDM1A
SCHEMBL2652188	0.87	PPARD (0.47)	GCGRGIPRGLP1RPPARDKDM1A
SCHEMBL2647399	0.87	PPARD (0.47)	GCGRGIPRGLP1RPPARDKDM1A
SCHEMBL2648952	0.86	GCGR (0.48)	GCGRGIPRPPARDSERPINE1APAF1
SCHEMBL2648950	0.86	GCGR (0.48)	GCGRGIPRPPARDSERPINE1APAF1
SCHEMBL2645893	0.85	GCGR (0.46)	GCGRGIPRSERPINE1APAF1BCL2L1
SCHEMBL2645898	0.85	GCGR (0.46)	GCGRGIPRSERPINE1APAF1BCL2L1
SCHEMBL2665061	0.85	GCGR (0.55)	GCGRGIPRGLP1RPPARDSERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2003048109-A1	NOVEL GLUCAGON ANTAGONISTS	NOVO NORDISK A/S (DK)	2003-06-12	—	—	WO	disclosed