Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.53 |
| ▸ | ADCY6 | O43306 | 6/20 | 0.49 |
| ▸ | ADCY3 | O60266 | 6/20 | 0.49 |
| ▸ | ADCY9 | O60503 | 6/20 | 0.49 |
| ▸ | ADCY5 | O95622 | 6/20 | 0.49 |
| ▸ | ADCY8 | P40145 | 6/20 | 0.49 |
| ▸ | ADCY7 | P51828 | 6/20 | 0.49 |
| ▸ | ADCY2 | Q08462 | 6/20 | 0.49 |
| ▸ | ADCY1 | Q08828 | 6/20 | 0.49 |
| ▸ | ADCY4 | Q8NFM4 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071409 | 0.92 | GCGR (0.54) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665111 | 0.89 | GCGR (0.58) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665033 | 0.89 | GCGR (0.56) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4092719 | 0.86 | SMN1; SMN2 (0.48) | GCGRSMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL2665095 | 0.86 | GCGR (0.61) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665156 | 0.85 | GCGR (0.52) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665102 | 0.85 | GCGR (0.63) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4092712 | 0.84 | GCGR (0.69) | GCGRSMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL9071460 | 0.84 | GCGR (0.61) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2665182 | 0.83 | GCGR (0.69) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |