SCHEMBL2665381

SCHEMBL2665381

N=C(Nc1ccc(OC(F)(F)F)cc1)N(Cc1ccc(C(=O)NC[C@@H](O)C(=O)O)cc1)c1ccc(C2CCCCC2)cc1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.67
GIPR P48546 15/20 0.67
GLP1R P43220 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2651584 0.92 GCGR (0.78) GCGRGIPRGLP1R
SCHEMBL2665376 0.88 GCGR (0.85) GCGRGIPRGLP1R
SCHEMBL9070986 0.88 GCGR (0.65) GCGRGIPRGLP1R
SCHEMBL2665456 0.88 GCGR (0.65) GCGRGIPRGLP1R
SCHEMBL2652606 0.88 GCGR (0.62) GCGRGIPR
SCHEMBL2652600 0.88 GCGR (0.62) GCGRGIPR
SCHEMBL2665429 0.87 GCGR (0.62) GCGRGIPRGLP1R
SCHEMBL2665366 0.87 GCGR (0.74) GCGRGIPRGLP1R
SCHEMBL2665377 0.85 GCGR (0.66) GCGRGIPRGLP1R
SCHEMBL9071841 0.85 GCGR (0.78) GCGRGIPRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed