SCHEMBL2665489

SCHEMBL2665489

CC(=O)c1cccc(NC(=O)N(Cc2ccc(C(=O)NC[C@@H](O)C(=O)O)cc2)c2ccc(C3CCCCC3)cc2)c1

nearest known ligand 0.83

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.83
GIPR P48546 18/20 0.83
GLP1R P43220 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2652811 0.92 GCGR (0.78) GCGRGIPRGLP1R
SCHEMBL2652808 0.92 GCGR (0.78) GCGRGIPRGLP1R
SCHEMBL9071702 0.91 GCGR (0.83) GCGRGIPRGLP1R
SCHEMBL2651415 0.91 GCGR (1.00) GCGRGIPRGLP1R
SCHEMBL2665517 0.91 GCGR (0.83) GCGRGIPRGLP1R
SCHEMBL2651417 0.91 GCGR (1.00) GCGRGIPRGLP1R
SCHEMBL2653328 0.90 GCGR (1.00) GCGRGIPRGLP1R
SCHEMBL2651349 0.90 GCGR (1.00) GCGRGIPRGLP1R
SCHEMBL7574026 0.90 GCGR (1.00) GCGRGIPRGLP1R
SCHEMBL2653336 0.90 GCGR (1.00) GCGRGIPRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002000612-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2002-01-03 WO disclosed