Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.47 |
| ▸ | GIPR | P48546 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651211 | 0.82 | GCGR (0.56) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2652185 | 0.77 | GCGR (0.60) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2653392 | 0.76 | GCGR (0.48) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2652304 | 0.75 | GCGR (0.50) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL7116449 | 0.74 | GCGR (0.50) | GCGRGIPRIDH1 | |
| SCHEMBL2652327 | 0.72 | PTGER4 (0.49) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2654491 | 0.70 | NAMPT (0.51) | GCGRCYP3A4CYP2C9IDH1 | |
| SCHEMBL2651576 | 0.70 | EGLN1 (0.48) | GCGR | |
| SCHEMBL2652296 | 0.69 | PPARG (0.49) | GCGR | |
| SCHEMBL2653039 | 0.69 | MRGPRX1 (0.51) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053938-A1 | BENZIMIDAZOLS AND INDOLS AS GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTEN | NOVO NORDISK A/S (DK) | 2003-07-03 | — | — | WO | disclosed |