Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26654487 | 0.89 | PDE1B (0.35) | — | |
| SCHEMBL26654802 | 0.86 | PTGER4 (0.35) | ALOX5APFEN1MBOAT4MEN1USP2 | |
| SCHEMBL26654532 | 0.86 | FYN (0.37) | MAPTPTGER4 | |
| SCHEMBL26654649 | 0.78 | MAPT (0.39) | MAPTKMT2APTGER4 | |
| SCHEMBL26654848 | 0.74 | ALOX5AP (0.36) | ALOX5APFEN1MEN1USP2MAPT | |
| SCHEMBL26655014 | 0.70 | PTGER4 (0.36) | ALOX5APFEN1MEN1USP2MAPT | |
| SCHEMBL26654832 | 0.69 | MAPT (0.41) | MAPTPTGER4 | |
| SCHEMBL24344353 | 0.68 | ALOX5AP (0.39) | ALOX5APFEN1MEN1USP2MAPT | |
| SCHEMBL22864666 | 0.67 | POLB (0.44) | MEN1MAPTKMT2A | |
| SCHEMBL28627251 | 0.67 | AAK1 (0.41) | MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524139-A1 | IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-117069725-A | Imidazopyridazine substituted benzene ring derivative, preparation method, pharmaceutical composition and application | 上海赛默罗生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023216753-A1 | IMIDAZOPYRIDAZINE SUBSTITUTED BENZENE RING DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 上海赛默罗生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |