Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.51 |
| ▸ | GIPR | P48546 | 14/20 | 0.51 |
| ▸ | GLP1R | P43220 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648701 | 0.82 | GCGR (0.58) | GCGRGIPRGLP1RNPC1RAB9A | |
| SCHEMBL9071343 | 0.81 | GCGR (0.42) | GCGRGIPRGLP1RHDAC1PPARG | |
| SCHEMBL2665606 | 0.80 | GCGR (0.66) | GCGRGIPRGLP1RHDAC1 | |
| SCHEMBL2665614 | 0.78 | GCGR (0.82) | GCGRGIPRGLP1R | |
| SCHEMBL2665558 | 0.78 | GCGR (0.71) | GCGRGIPRGLP1R | |
| SCHEMBL2665585 | 0.78 | GCGR (0.71) | GCGRGIPRGLP1R | |
| SCHEMBL9071732 | 0.78 | GCGR (0.55) | GCGRGIPRGLP1RNPC1RAB9A | |
| SCHEMBL2653992 | 0.78 | CA1 (0.61) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2643601 | 0.78 | CA1 (0.61) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2649311 | 0.77 | GCGR (0.47) | GCGRGIPRGLP1RHDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000612-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-01-03 | — | — | WO | disclosed |