SCHEMBL2665571

SCHEMBL2665571

O=C(NC[C@@H](O)C(=O)O)c1ccc(CN(C(=O)Nc2nc3cc(OC(F)(F)F)ccc3s2)c2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.61
GIPR P48546 17/20 0.61
GLP1R P43220 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665581 0.95 GCGR (0.61) GCGRGIPRGLP1R
SCHEMBL2665751 0.91 GCGR (0.66) GCGRGIPRGLP1R
SCHEMBL2658602 0.90 GCGR (0.75) GCGRGIPRGLP1R
SCHEMBL2665652 0.89 GCGR (0.74) GCGRGIPRGLP1R
SCHEMBL2665643 0.88 GCGR (0.72) GCGRGIPRGLP1R
SCHEMBL2665749 0.88 GCGR (0.70) GCGRGIPRGLP1R
SCHEMBL2665578 0.88 GCGR (0.73) GCGRGIPRGLP1R
SCHEMBL2665589 0.87 GCGR (0.62) GCGRGIPRGLP1R
SCHEMBL9071774 0.86 GCGR (0.60) GCGRGIPRGLP1R
SCHEMBL2665624 0.86 GCGR (0.63) GCGRGIPRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002000612-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2002-01-03 WO disclosed