⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266558 | 0.85 | — | — | |
| SCHEMBL15163727 | 0.72 | — | — | |
| SCHEMBL24282501 | 0.69 | — | — | |
| SCHEMBL14226921 | 0.69 | — | — | |
| SCHEMBL11744611 | 0.68 | — | — | |
| SCHEMBL2302701 | 0.68 | — | — | |
| SCHEMBL13626381 | 0.68 | — | — | |
| SCHEMBL10074975 | 0.68 | — | — | |
| SCHEMBL24749624 | 0.68 | — | — | |
| SCHEMBL262126 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777069-B2 | Compositions and methods for detection of methadone metabolite | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20140221626-A1 | COMPOSITIONS AND METHODS FOR DETECTION OF METHADONE METABOLITE | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8771964-B2 | Compositions and methods for detection of methadone metabolite | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-8629126-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC. (JP) | 2014-01-14 | — | — | US | disclosed |
| US-8629126-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC. (JP) | 2014-01-14 | — | — | US | disclosed |
| US-20130203076-A1 | COMPOSITIONS AND METHODS FOR DETECTION OF METHADONE METABOLITE | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-1995240-B1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-02-22 | — | — | EP | disclosed |
| EP-2418213-A1 | NEUROMEDIN U DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-02-15 | — | — | EP | disclosed |
| US-20090197834-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | US | disclosed |
| US-20090197834-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-1995240-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-4353913-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0010242-B1 | BENZIMIDAZOLYL-2-CARBAMIC ACID ESTERS, MEDICAMENTS BASED THEREON AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4287199-A | USEFUL AS ANTHELMINITICS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-01 | — | — | US | disclosed |
| EP-0010242-A1 | Benzimidazolyl-2-carbamic acid esters, medicaments based thereon and process for their preparation | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |