Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106683 | 0.88 | APP (0.36) | APPBCHEACHEBCDIN3DKMT2A | |
| SCHEMBL9235181 | 0.86 | BCDIN3D (0.37) | APPBCHEACHEBCDIN3DKMT2A | |
| SCHEMBL9103257 | 0.86 | APP (0.35) | APPBCHEACHEBCDIN3DKMT2A | |
| Hydrochloric Acid SCHEMBL9235340 | 0.85 | BCDIN3D (0.36) | APPBCHEACHEBCDIN3DKMT2A | |
| SCHEMBL9235868 | 0.84 | CYP1A2 (0.35) | APPBCHEACHEBCDIN3DKMT2A | |
| Hydrochloric Acid SCHEMBL13837724 | 0.82 | CYP1A2 (0.34) | APPBCHEACHEBCDIN3DKMT2A | |
| SCHEMBL9102572 | 0.79 | APP (0.43) | APPBCHEACHEBCDIN3DKMT2A | |
| SCHEMBL9104836 | 0.78 | APP (0.48) | APPBCHEACHEBCDIN3DKMT2A | |
| SCHEMBL9912559 | 0.78 | MEN1 (0.40) | APPBCHEACHEKMT2AMEN1 | |
| SCHEMBL9238122 | 0.78 | APP (0.40) | APPBCHEACHEBCDIN3DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225177-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT RESPIRATORY DEPRESSION IN PATIENTS | ENALARE THERAPEUTICS INC. (US) | 2023-11-23 | — | — | WO | disclosed |