SCHEMBL2665641

SCHEMBL2665641

Cc1ccc(NC(=O)N(Cc2ccc(C(=O)NC[C@@H](O)C(=O)O)cc2)c2ccc(C3CCCCC3)cc2)cc1Br

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.78
GIPR P48546 18/20 0.78
GLP1R P43220 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9071697 0.91 GCGR (0.79) GCGRGIPRGLP1R
SCHEMBL9071704 0.89 GCGR (0.79) GCGRGIPRGLP1R
SCHEMBL2665638 0.89 GCGR (0.81) GCGRGIPRGLP1R
SCHEMBL2665492 0.89 GCGR (0.72) GCGRGIPRGLP1R
SCHEMBL2665656 0.88 GCGR (0.82) GCGRGIPRGLP1R
SCHEMBL2665511 0.88 GCGR (0.86) GCGRGIPRGLP1R
SCHEMBL2663406 0.88 GCGR (0.68) GCGRGIPRGLP1R
SCHEMBL2651415 0.88 GCGR (1.00) GCGRGIPRGLP1R
SCHEMBL2651417 0.88 GCGR (1.00) GCGRGIPRGLP1R
SCHEMBL2665531 0.87 GCGR (0.81) GCGRGIPRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002000612-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2002-01-03 WO disclosed