Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.64 |
| ▸ | GIPR | P48546 | 12/20 | 0.62 |
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071337 | 0.92 | GCGR (0.64) | GCGRGIPRGLP1RSTAT3HDAC3 | |
| SCHEMBL9071332 | 0.90 | GCGR (0.62) | GCGRGIPRGLP1RSTAT3 | |
| SCHEMBL2665718 | 0.90 | GCGR (0.80) | GCGRGIPRGLP1RSTAT3 | |
| SCHEMBL9071334 | 0.88 | GCGR (0.60) | GCGRGIPRGLP1RSTAT3 | |
| SCHEMBL9071354 | 0.88 | GCGR (0.60) | GCGRGIPRGLP1RSTAT3 | |
| SCHEMBL9071363 | 0.88 | GCGR (0.60) | GCGRGIPRGLP1RSTAT3 | |
| SCHEMBL2665695 | 0.88 | GCGR (0.73) | GCGRGIPRGLP1RSTAT3 | |
| SCHEMBL9071339 | 0.88 | GCGR (0.63) | GCGRGIPRGLP1RSTAT3 | |
| SCHEMBL2665923 | 0.86 | GCGR (0.61) | GCGRGIPRSTAT3 | |
| SCHEMBL2665931 | 0.86 | GCGR (0.63) | GCGRGIPRGLP1RSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040446-A1 | GLUCAGON ANTAGONIST/INVERSE AGONIST | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |