Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.74 |
| ▸ | GIPR | P48546 | 7/20 | 0.74 |
| ▸ | GLP1R | P43220 | 3/20 | 0.65 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.59 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.59 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.59 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.59 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.59 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.59 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.59 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.59 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665919 | 0.95 | GCGR (0.79) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL9071322 | 0.92 | GCGR (0.79) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL9071366 | 0.88 | GCGR (0.77) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2663034 | 0.87 | GCGR (0.82) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665598 | 0.86 | GCGR (0.83) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL6289552 | 0.85 | GCGR (1.00) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665469 | 0.85 | GCGR (1.00) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL6289550 | 0.85 | GCGR (1.00) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665799 | 0.83 | GCGR (0.85) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2659665 | 0.83 | GCGR (1.00) | GCGRGIPRGLP1RADCY6ADCY3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040446-A1 | GLUCAGON ANTAGONIST/INVERSE AGONIST | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |