Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.49 |
| ▸ | GIPR | P48546 | 16/20 | 0.49 |
| ▸ | GLP1R | P43220 | 6/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.44 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.44 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.44 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.44 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.44 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.44 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071376 | 0.92 | GCGR (0.57) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665782 | 0.90 | GCGR (0.48) | GCGRGIPRGLP1R | |
| SCHEMBL9071377 | 0.90 | GCGR (0.50) | GCGRGIPRGLP1R | |
| SCHEMBL9071374 | 0.90 | GCGR (0.51) | GCGRGIPRGLP1R | |
| SCHEMBL2665727 | 0.90 | GCGR (0.54) | GCGRGIPRGLP1R | |
| SCHEMBL2665709 | 0.90 | GCGR (0.58) | GCGRGIPRGLP1R | |
| SCHEMBL2665792 | 0.88 | GCGR (0.47) | GCGRGIPRGLP1R | |
| SCHEMBL2665707 | 0.88 | GCGR (0.53) | GCGRGIPRGLP1R | |
| SCHEMBL9071331 | 0.88 | GCGR (0.59) | GCGRGIPRGLP1R | |
| SCHEMBL2665728 | 0.88 | GCGR (0.49) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040446-A1 | GLUCAGON ANTAGONIST/INVERSE AGONIST | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |