SCHEMBL26658010

SCHEMBL26658010

CCc1cc(C(C)C)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.46
RAB9A P51151 8/20 0.46
POLB P06746 3/20 0.44
LMNA P02545 2/20 0.42
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 7/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
IDH1 O75874 1/20 0.35
CASP3 P42574 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20363907 0.90 NPC1 (0.47) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26658018 0.89 NPC1 (0.44) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26658064 0.87 NPC1 (0.42) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26658078 0.86 NPC1 (0.41) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL14324336 0.85 IDH1 (0.44) NPC1RAB9APOLBLMNAIDH1
SCHEMBL9408813 0.85 NPC1 (0.40) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26658001 0.85 NPC1 (0.40) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26658047 0.85 NPC1 (0.40) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26658058 0.85 NPC1 (0.40) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26657995 0.85 NPC1 (0.40) NPC1RAB9APOLBLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240110120-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY CHEVRON U.S.A. INC. (US) 2024-04-04 US claimed
EP-4281528-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY Chevron U.S.A. Inc. (US) 2023-11-29 EP claimed
US-20240110120-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY CHEVRON U.S.A. INC. (US) 2024-04-04 US disclosed
EP-4281528-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY Chevron U.S.A. Inc. (US) 2023-11-29 EP disclosed