SCHEMBL2665829

SCHEMBL2665829

O=C(O)CCNC(=O)c1ccc(CN(CCc2cccs2)c2nc(-c3ccc(OC(F)(F)F)cc3)cs2)cc1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.71
GIPR P48546 18/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665776 0.92 GCGR (0.67) GCGRGIPR
SCHEMBL9071178 0.89 GCGR (0.68) GCGRGIPR
SCHEMBL2665737 0.86 GCGR (0.61) GCGRGIPR
SCHEMBL2647489 0.84 GCGR (0.94) GCGRGIPR
SCHEMBL13109439 0.84 GCGR (0.57) GCGRGIPR
Hydrochloric Acid SCHEMBL3453450 0.83 GCGR (0.56) GCGRGIPR
SCHEMBL2665878 0.83 GCGR (0.88) GCGRGIPR
SCHEMBL2648635 0.83 GCGR (1.00) GCGRGIPR
SCHEMBL2648158 0.83 GCGR (0.88) GCGRGIPR
SCHEMBL2665892 0.81 GCGR (0.87) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004002480-A1 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed