SCHEMBL2665840

SCHEMBL2665840

CC(C)(C)c1ccc(N(Cc2ccc(C(=O)NCCC(=O)O)cc2)c2nc(-c3ccc(C#N)cc3)cs2)cc1

nearest known ligand 0.87

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.87
GIPR P48546 20/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2655033 0.93 GCGR (1.00) GCGRGIPR
SCHEMBL2655301 0.90 GCGR (0.92) GCGRGIPR
SCHEMBL6134667 0.90 GCGR (0.92) GCGRGIPR
SCHEMBL2665812 0.88 GCGR (0.83) GCGRGIPR
SCHEMBL2665785 0.86 GCGR (0.88) GCGRGIPR
SCHEMBL2665874 0.86 GCGR (1.00) GCGRGIPR
SCHEMBL6134943 0.86 GCGR (0.84) GCGRGIPR
SCHEMBL6135592 0.85 GCGR (0.83) GCGRGIPR
SCHEMBL2665852 0.85 GCGR (0.80) GCGRGIPR
SCHEMBL6135048 0.85 GCGR (0.82) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004002480-A1 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed