SCHEMBL2665858

SCHEMBL2665858

Bc1ccc(N(Cc2ccc(C(=O)NCCC(=O)O)cc2)c2nc(-c3ccccc3)cs2)cc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.76
GIPR P48546 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647863 0.91 GCGR (0.76) GCGRGIPR
SCHEMBL2649741 0.89 GCGR (0.83) GCGRGIPR
SCHEMBL2649061 0.89 GCGR (0.76) GCGRGIPR
SCHEMBL2665860 0.87 GCGR (0.65) GCGRGIPR
SCHEMBL2647280 0.87 GCGR (0.88) GCGRGIPR
SCHEMBL9071189 0.87 GCGR (0.74) GCGRGIPR
SCHEMBL2647753 0.86 GCGR (1.00) GCGRGIPR
SCHEMBL2657653 0.86 GCGR (0.73) GCGRGIPR
SCHEMBL2648785 0.86 GCGR (0.98) GCGRGIPR
SCHEMBL2655033 0.85 GCGR (1.00) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004002480-A1 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed