SCHEMBL2665865

SCHEMBL2665865

CCc1ccc(N(Cc2ccc(C(=O)NCCC(=O)O)cc2)c2nc(-c3ccc(Cl)cc3)cs2)cc1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.81
GIPR P48546 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647280 0.96 GCGR (0.88) GCGRGIPR
SCHEMBL2648168 0.93 GCGR (0.79) GCGRGIPR
SCHEMBL2649088 0.93 GCGR (0.81) GCGRGIPR
SCHEMBL2649741 0.92 GCGR (0.83) GCGRGIPR
SCHEMBL2647095 0.92 GCGR (0.77) GCGRGIPR
SCHEMBL2655301 0.92 GCGR (0.92) GCGRGIPR
SCHEMBL2647334 0.91 GCGR (0.81) GCGRGIPR
SCHEMBL2647749 0.91 GCGR (0.76) GCGRGIPR
SCHEMBL2648745 0.90 GCGR (0.75) GCGRGIPR
SCHEMBL2649736 0.90 GCGR (1.00) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004002480-A1 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed