SCHEMBL2665992

SCHEMBL2665992

O=C(O)CCNC(=O)c1ccc(CN(c2ccc(Br)cc2)c2nc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cs2)cc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.75
GIPR P48546 19/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647606 0.94 GCGR (0.85) GCGRGIPR
SCHEMBL2665866 0.94 GCGR (0.85) GCGRGIPR
SCHEMBL2666028 0.94 GCGR (0.85) GCGRGIPR
SCHEMBL2647343 0.94 GCGR (0.85) GCGRGIPR
SCHEMBL6135592 0.92 GCGR (0.83) GCGRGIPR
SCHEMBL2647463 0.92 GCGR (0.88) GCGRGIPR
SCHEMBL2648112 0.91 GCGR (0.75) GCGRGIPR
SCHEMBL2646896 0.90 GCGR (0.88) GCGRGIPR
SCHEMBL2647355 0.90 GCGR (0.88) GCGRGIPR
SCHEMBL6135050 0.89 GCGR (0.75) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004002480-A1 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed