SCHEMBL2666090

SCHEMBL2666090

Bc1cnc(NC(=O)C(CC2CCOCC2)c2ccc(S(C)(=O)=O)cc2)s1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2657502 0.91 GCK (0.80) GCK
SCHEMBL2651227 0.90 GCK (0.84) GCK
SCHEMBL2660018 0.89 GCK (0.80) GCK
SCHEMBL2658457 0.89 GCK (1.00) GCK
SCHEMBL2650597 0.89 GCK (0.80) GCK
SCHEMBL2651072 0.89 GCK (0.80) GCK
SCHEMBL2657712 0.89 GCK (0.80) GCK
SCHEMBL2650460 0.89 GCK (1.00) GCK
SCHEMBL2650657 0.88 GCK (0.79) GCK
SCHEMBL2651276 0.87 GCK (0.77) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2168962-A2 PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS Prosidion Limited (GB) 2010-03-31 EP disclosed
WO-2004072031-A2 PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS PROSIDION LIMITED (GB) 2004-08-26 WO disclosed