Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.67 |
| ▸ | NOS2 | P35228 | 5/20 | 0.46 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ARG2 | P78540 | 4/20 | 0.43 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL26662021 | 1.00 | GSR (0.67) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL124168 | 0.93 | GSR (0.53) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL7112527 | 0.93 | GSR (0.53) | GSRNOS2NOS1NOS3CYP1A2 | |
| Water SCHEMBL28009501 | 0.91 | GSR (0.52) | GSRRNPEPCPB2 | |
| Hydrochloric Acid SCHEMBL27742346 | 0.90 | GSR (0.50) | GSRNOS2NOS1BLMRNPEP | |
| Lysine SCHEMBL28806096 | 0.88 | GSR (0.74) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL535529 | 0.88 | GSR (0.45) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL28976026 | 0.84 | GSR (0.74) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL9547132 | 0.84 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 | |
| Lysine SCHEMBL7131633 | 0.84 | GSR (0.87) | GSRNOS2NOS1NOS3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117106013-A | Polylysine salt and purification method thereof | 北京诺康达医药科技股份有限公司 | 2023-11-24 | — | — | CN | claimed |
| WO-2023221978-A1 | POLYLYSINE SALT, PREPARATION METHOD THEREFOR, AND PURIFICATION METHOD THEREFOR | 北京诺康达医药科技股份有限公司 | 2023-11-23 | — | — | WO | claimed |
| US-20250295585-A1 | THERAPEUTIC HYDROGELS | BOSTON SCIENTIFIC SCIMED INC. (US) | 2025-09-25 | — | — | US | disclosed |
| US-12343426-B2 | Therapeutic hydrogels | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-07-01 | — | — | US | disclosed |
| EP-4288103-A1 | THERAPEUTIC HYDROGELS | Boston Scientific Scimed Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-117106013-A | Polylysine salt and purification method thereof | 北京诺康达医药科技股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117106014-A | Trilysine acetate and preparation method and application thereof | 北京诺康达医药科技股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120094-A | Therapeutic hydrogels | 波士顿科学国际有限公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2023221978-A1 | POLYLYSINE SALT, PREPARATION METHOD THEREFOR, AND PURIFICATION METHOD THEREFOR | 北京诺康达医药科技股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| WO-2022216691-A1 | THERAPEUTIC HYDROGELS | BOSTON SCIENTIFIC SCIMED INC. (US) | 2022-10-13 | — | — | WO | disclosed |
| US-20220313603-A1 | THERAPEUTIC HYDROGELS | BOSTON SCIENTIFIC SCIMED INC. (US) | 2022-10-06 | — | — | US | disclosed |