Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GIPR | P48546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660761 | 0.93 | GCGR (0.43) | SERPINE1DHODHBCL2L1MCL1GCGR | |
| SCHEMBL2666470 | 0.84 | PPARD (0.45) | DHODHBCL2L1MCL1GCGRHAO1 | |
| SCHEMBL2653731 | 0.83 | HAO1 (0.46) | BCL2L1MCL1GCGRHAO1EPHX2 | |
| SCHEMBL2665081 | 0.83 | GCGR (0.49) | SERPINE1BCL2L1MCL1GCGRGLP1R | |
| SCHEMBL2659967 | 0.81 | GCGR (0.47) | SERPINE1BCL2L1MCL1GCGRHAO1 | |
| SCHEMBL2647125 | 0.81 | CYP2D6 (0.45) | BCL2L1MCL1GCGRHAO1GLP1R | |
| SCHEMBL2647381 | 0.80 | GCGR (0.48) | SERPINE1BCL2L1MCL1GCGRHAO1 | |
| SCHEMBL2646962 | 0.80 | GCGR (0.44) | SERPINE1BCL2L1MCL1GCGRHAO1 | |
| SCHEMBL2654474 | 0.79 | HAO1 (0.42) | BCL2L1MCL1GCGRHAO1EPHX2 | |
| SCHEMBL2653410 | 0.79 | CYP2D6 (0.44) | BCL2L1MCL1GCGRHAO1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |