Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 8/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795449 | 0.92 | GCK (0.48) | GCKRARARARBRARGSPHK2 | |
| SCHEMBL14018651 | 0.90 | GCK (0.54) | GCKRARARARBRARGSPHK2 | |
| SCHEMBL1792248 | 0.82 | GCK (0.54) | GCKRARARARBRARGMEN1 | |
| SCHEMBL1794120 | 0.82 | GCK (0.49) | GCKRARARARBRARGMEN1 | |
| SCHEMBL2666435 | 0.81 | GCK (0.48) | GCKRARARARBRARGSPHK2 | |
| SCHEMBL2664858 | 0.81 | GCK (0.57) | GCKRARARARBRARGSPHK2 | |
| SCHEMBL5134807 | 0.80 | GCK (0.47) | GCKRARARARBRARG | |
| SCHEMBL2664602 | 0.78 | GCK (0.56) | GCKRARARARBRARGSPHK2 | |
| SCHEMBL2664864 | 0.77 | GCK (0.53) | GCKRARARARBRARGSPHK2 | |
| SCHEMBL2664861 | 0.77 | GCK (0.51) | GCKRARARARBRARGSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003015774-A1 | COMPOUNDS EFFECTING GLUCOKINASE | ASTRAZENECA AB (SE) | 2003-02-27 | — | — | WO | disclosed |