Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.63 |
| ▸ | GIPR | P48546 | 9/20 | 0.52 |
| ▸ | STAT3 | P40763 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4087809 | 0.88 | GCGR (0.61) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL4081881 | 0.88 | GCGR (0.61) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2663366 | 0.88 | GCGR (0.61) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL9070861 | 0.83 | GCGR (0.65) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL6755480 | 0.83 | GCGR (0.65) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2650887 | 0.83 | GCGR (0.59) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2663310 | 0.83 | GCGR (0.61) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2653321 | 0.82 | GCGR (0.61) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2660467 | 0.82 | GCGR (0.73) | GCGRGIPRGLP1R | |
| SCHEMBL2663249 | 0.82 | GCGR (0.62) | GCGRGIPRSTAT3OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |