Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 8/20 | 0.67 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28751562 | 1.00 | PLA2G2C (0.67) | PLA2G2CPLA2G2ASIRT6SIRT1CA2 | |
| SCHEMBL30887481 | 0.98 | PLA2G2C (0.64) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL19271824 | 0.98 | PLA2G2C (0.64) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL27334118 | 0.98 | PLA2G2C (0.64) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL19271786 | 0.98 | PLA2G2C (0.64) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL11606057 | 0.98 | PLA2G2C (0.64) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL6940595 | 0.98 | PLA2G2C (0.64) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL10576657 | 0.98 | PLA2G2C (0.64) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL19412266 | 0.94 | PLA2G2C (0.60) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 | |
| SCHEMBL17193095 | 0.94 | PLA2G2C (0.60) | PLA2G2CPLA2G2ASIRT6SIRT1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045614-A1 | QUINOLINE DERIVATIVES AS GLUCOKINASE LIGANDS | ASTRAZENECA AB (SE) | 2004-06-03 | — | — | WO | disclosed |