Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775213 | 0.93 | GCK (0.46) | GCKKCNH2RARG | |
| SCHEMBL1775212 | 0.92 | GCK (0.47) | GCKKCNH2RARG | |
| SCHEMBL1775913 | 0.87 | GCK (0.46) | GCKKCNH2RARG | |
| SCHEMBL1775912 | 0.86 | GCK (0.47) | GCKKCNH2RARG | |
| SCHEMBL1774974 | 0.85 | GCK (0.48) | GCKKCNH2RARG | |
| SCHEMBL1774973 | 0.84 | GCK (0.48) | GCKKCNH2RARG | |
| SCHEMBL1775511 | 0.81 | GCK (0.59) | GCKKCNH2RARG | |
| SCHEMBL1775508 | 0.80 | GCK (0.60) | GCKKCNH2RARG | |
| SCHEMBL9072493 | 0.79 | GCK (0.48) | GCKKCNH2RARG | |
| SCHEMBL1774688 | 0.79 | GCK (0.49) | GCKKCNH2RARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125972-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |