Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.47 |
| ▸ | GIPR | P48546 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251967 | 0.82 | GCGR (0.60) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2252432 | 0.81 | GCGR (0.58) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2667435 | 0.80 | GCGR (0.46) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL12360378 | 0.79 | GCGR (0.56) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL13003075 | 0.78 | GCGR (0.47) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2254585 | 0.69 | GCGR (0.59) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9071633 | 0.68 | GCGR (0.81) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2255779 | 0.68 | GCGR (0.59) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2667313 | 0.67 | GCGR (0.76) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL12360373 | 0.67 | GCGR (0.54) | GCGRGIPRCYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069158-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2004-08-19 | — | — | WO | disclosed |