SCHEMBL2667765

SCHEMBL2667765

COc1ccc(Oc2cc(C(=O)Nc3ccc(C(=O)O)cn3)cc(OC(C)C)n2)cc1

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.65
RARA P10276 1/20 0.58
RARB P10826 1/20 0.58
RARG P13631 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9070998 0.91 GCK (0.63) GCKRARARARBRARG
SCHEMBL9071029 0.89 GCK (0.78) GCKRARARARBRARG
SCHEMBL2656899 0.89 GCK (0.62) GCKRARARARBRARG
SCHEMBL2667725 0.89 GCK (0.66) GCKRARARARBRARG
SCHEMBL2667621 0.89 GCK (0.61) GCKRARARARBRARG
SCHEMBL2667767 0.89 GCK (0.61) GCKRARARARBRARG
SCHEMBL2667362 0.88 GCK (0.60) GCKRARARARBRARG
SCHEMBL2667440 0.88 GCK (0.66) GCKRARARARBRARG
SCHEMBL2667685 0.87 GCK (0.65) GCKRARARARBRARG
SCHEMBL9071043 0.87 GCK (0.58) GCKRARARARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009083553-A1 AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS RHEOSCIENCE A/S (DK) 2009-07-09 WO disclosed