Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26027305 | 1.00 | AKT1 (0.42) | AKT1ALDH1A1SMN1; SMN2EPHX2ACE | |
| SCHEMBL26027432 | 1.00 | AKT1 (0.42) | AKT1ALDH1A1SMN1; SMN2EPHX2ACE | |
| SCHEMBL26503041 | 0.87 | AKT1 (0.47) | AKT1ALDH1A1SMN1; SMN2FAAHOPRD1 | |
| SCHEMBL24037988 | 0.87 | AKT1 (0.44) | AKT1ALDH1A1SMN1; SMN2ACEACE2 | |
| SCHEMBL25000276 | 0.85 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HRH1OPRD1 | |
| SCHEMBL31365048 | 0.84 | AKT1 (0.39) | AKT1EPHX2HRH1OPRD1 | |
| SCHEMBL26348504 | 0.84 | AKT1 (0.45) | AKT1ALDH1A1SMN1; SMN2OPRD1 | |
| SCHEMBL23630030 | 0.84 | AKT1 (0.48) | AKT1ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL23630027 | 0.84 | AKT1 (0.48) | AKT1ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL25873361 | 0.84 | AKT1 (0.48) | AKT1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265620-A1 | NOVEL CAMPTOTHECIN DERIVATIVE, COMPOSITION CONTAINING SAME, AND USE THEREOF | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |