SCHEMBL26679019

SCHEMBL26679019

CC(C)CC(N)C(=O)NC(C)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)N(C)C)C3)[C@H](C)[C@H]12

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CACNA1C Q13936 1/20 0.49
ESR1 P03372 1/20 0.49
PTGS1 P23219 1/20 0.49
PDE4A P27815 1/20 0.49
ABCC2 Q92887 1/20 0.43
FAP Q12884 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22429138 1.00 CACNA1C (0.49) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL22429572 1.00 CACNA1C (0.49) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL22429896 1.00 CACNA1C (0.49) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL26678817 0.93 CACNA1C (0.50) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL22429540 0.93 CACNA1C (0.50) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL26678826 0.93 CACNA1C (0.50) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL26679014 0.91 ESR1 (0.49) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL19374295 0.91 ESR1 (0.51) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL22429130 0.91 ESR1 (0.49) CACNA1CESR1PTGS1PDE4AABCC2
SCHEMBL26679026 0.91 ESR1 (0.49) CACNA1CESR1PTGS1PDE4AABCC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3430013-B1 CARBAPENEM COMPOUNDS ORCHID PHARMA LTD (IN) 2023-11-15 EP disclosed