Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070945 | 0.93 | GCK (0.51) | GCKPRKAA2RARARARBRARG | |
| SCHEMBL9070907 | 0.93 | GCK (0.53) | GCKPRKAA2RARARARBRARG | |
| SCHEMBL2667347 | 0.93 | GCK (0.54) | GCKPRKAA2RARARARBRARG | |
| SCHEMBL9070951 | 0.92 | GCK (0.45) | GCKPRKAA2KDM4ERAB9ALRRK2 | |
| SCHEMBL2667480 | 0.92 | PRKAA2 (0.48) | GCKPRKAA2RARARARBRARG | |
| SCHEMBL9070813 | 0.85 | GCK (0.55) | GCKPRKAA2RARARARBRARG | |
| SCHEMBL2667785 | 0.85 | GCK (0.53) | GCKRARARARBRARG | |
| SCHEMBL9070835 | 0.85 | GCK (0.52) | GCKPRKAA2 | |
| SCHEMBL2667695 | 0.85 | GCK (0.50) | GCKPRKAA2 | |
| SCHEMBL9070909 | 0.84 | GCK (0.44) | GCKRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |