Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668009 | 0.90 | GRM5 (0.48) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL9071027 | 0.89 | MAPK1 (0.59) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2667799 | 0.88 | MAPK1 (0.55) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2667584 | 0.88 | MAPK1 (0.54) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2667791 | 0.87 | MAPT (0.56) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2667678 | 0.87 | MAPK1 (0.59) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2668000 | 0.86 | MAPT (0.63) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2667834 | 0.86 | MAPK1 (0.64) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2667815 | 0.86 | MAPK1 (0.57) | MAPK1HTTTSHRLMNAALDH1A1 | |
| SCHEMBL2667790 | 0.86 | MAPK1 (0.52) | MAPK1HTTTSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |