Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084508 | 1.00 | GCK (0.54) | GCK | |
| SCHEMBL2668057 | 0.91 | GCK (0.50) | GCK | |
| SCHEMBL2087509 | 0.91 | GCK (0.50) | GCK | |
| SCHEMBL9072504 | 0.90 | GCK (0.54) | GCK | |
| SCHEMBL2667853 | 0.90 | GCK (0.56) | GCK | |
| SCHEMBL2085412 | 0.90 | GCK (0.54) | GCK | |
| SCHEMBL2088328 | 0.90 | GCK (0.54) | GCK | |
| SCHEMBL2087663 | 0.86 | GCK (0.56) | GCK | |
| SCHEMBL2088244 | 0.83 | GCK (0.57) | GCK | |
| SCHEMBL9072505 | 0.83 | GCK (0.57) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125958-A1 | 2-PHENYL SUBSTITUTED IMIDAZOL [4 , 5B] PYRIDINE/ PYRAZINE AND PURINE DERIVATIVES AS GLUCOKINASE MODULATORS | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |