SCHEMBL26680309

O=C(O)c1cncc(-c2ccccc2CN2CCN(c3ccc(C(=O)N(c4ccc(NCCSc5ccccc5)c([N+](=O)[O-])c4)[SH](=O)=O)cc3)CC2)c1

nearest known ligand 0.48

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	BCL2L1	Q07817	20/20	0.48

▸	BCL2	P10415	11/20	0.48

▸	MDM4	O15151	1/20	0.44

▸	BCL2L11	O43521	1/20	0.44

▸	TP53	P04637	1/20	0.44

▸	BID	P55957	1/20	0.44

▸	BAX	Q07812	1/20	0.44

▸	MCL1	Q07820	1/20	0.44

▸	ASPH	Q12797	1/20	0.44

▸	BECN1	Q14457	1/20	0.44

▸	BAK1	Q16611	1/20	0.44

▸	BCL2L2	Q92843	1/20	0.44

▸	BAD	Q92934	1/20	0.44

▸	BBC3	Q9BXH1	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26680533	0.95	BCL2L1 (0.47)	BCL2L1BCL2MDM4BCL2L11TP53
SCHEMBL26683155	0.93	BCL2L1 (0.46)	BCL2L1BCL2MDM4BCL2L11TP53
SCHEMBL26680726	0.92	BCL2L1 (0.49)	BCL2L1BCL2MDM4BCL2L11TP53
SCHEMBL26682331	0.86	BCL2L1 (0.47)	BCL2L1BCL2
SCHEMBL26680320	0.84	BCL2L1 (0.66)	BCL2L1BCL2MDM4BCL2L11TP53
SCHEMBL26680540	0.80	BCL2L1 (0.65)	BCL2L1BCL2
SCHEMBL26683163	0.78	BCL2L1 (0.63)	BCL2L1BCL2MDM4BCL2L11TP53
SCHEMBL26681275	0.78	BCL2L1 (0.66)	BCL2L1BCL2MDM4BCL2L11TP53
SCHEMBL30963903	0.77	BCL2L1 (0.63)	BCL2L1BCL2
SCHEMBL26681055	0.77	BCL2L1 (0.63)	BCL2L1BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4279476-A1	METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP	CHUGAI SEIYAKU KABUSHIKI KAISHA (JP)	2023-11-22	—	—	EP	disclosed