Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.48 |
| ▸ | BCL2 | P10415 | 14/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202059 | 0.95 | BCL2L1 (0.49) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26682385 | 0.94 | BCL2L1 (0.47) | BCL2L1BCL2MCL1 | |
| SCHEMBL26682705 | 0.94 | BCL2L1 (0.51) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26681182 | 0.92 | BCL2L1 (0.48) | BCL2L1BCL2MCL1 | |
| SCHEMBL26681662 | 0.92 | BCL2L1 (0.49) | BCL2L1BCL2MCL1 | |
| SCHEMBL26681933 | 0.92 | BCL2L1 (0.50) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26681677 | 0.91 | BCL2L1 (0.49) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL30687565 | 0.90 | BCL2L1 (0.45) | BCL2L1BCL2 | |
| SCHEMBL26680761 | 0.90 | BCL2L1 (0.45) | BCL2L1BCL2 | |
| SCHEMBL26682690 | 0.90 | BCL2L1 (0.48) | BCL2L1BCL2MCL1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | BCL2L1 650/4885BCL2 131/4885MCL1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.