Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.51 |
| ▸ | BCL2 | P10415 | 15/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30687653 | 1.00 | BCL2L1 (0.51) | BCL2L1BCL2MCL1BAK1AURKA | |
| SCHEMBL26681087 | 0.93 | BCL2L1 (0.52) | BCL2L1BCL2MCL1BAK1AURKA | |
| SCHEMBL26682690 | 0.91 | BCL2L1 (0.48) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26681180 | 0.90 | BCL2L1 (0.45) | BCL2L1BCL2MCL1 | |
| SCHEMBL26680872 | 0.90 | BCL2L1 (0.52) | BCL2L1BCL2MCL1BAK1AURKA | |
| SCHEMBL26682146 | 0.89 | BCL2L1 (0.51) | BCL2L1BCL2MCL1 | |
| SCHEMBL26681943 | 0.89 | BCL2L1 (0.66) | BCL2L1BCL2MCL1BAK1AURKA | |
| SCHEMBL26681933 | 0.88 | BCL2L1 (0.50) | BCL2L1BCL2MCL1BAK1AURKA | |
| SCHEMBL26681941 | 0.88 | BCL2L1 (0.49) | BCL2L1BCL2MCL1 | |
| SCHEMBL30687632 | 0.88 | BCL2L1 (0.50) | BCL2L1BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |