Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.59 |
| ▸ | BCL2 | P10415 | 12/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.49 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26680350 | 0.95 | BCL2L1 (0.63) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26680937 | 0.94 | BCL2L1 (0.61) | BCL2L1BCL2MCL1BCL2L2 | |
| SCHEMBL26681944 | 0.94 | BCL2L1 (0.59) | BCL2L1BCL2MCL1BAK1BCL2L2 | |
| SCHEMBL26683299 | 0.93 | BCL2L1 (0.59) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26681585 | 0.92 | BCL2L1 (0.61) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26682076 | 0.92 | BCL2L1 (0.47) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL26680856 | 0.91 | BCL2L1 (0.61) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26680739 | 0.90 | BCL2L1 (0.46) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26683127 | 0.89 | BCL2L1 (0.66) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL26682178 | 0.89 | BCL2L1 (0.49) | BCL2L1BCL2BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |