Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 4/20 | 0.48 |
| ▸ | GCK | P35557 | 11/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657739 | 0.82 | GCK (0.58) | GCK | |
| SCHEMBL2658947 | 0.79 | POLB (0.44) | FFAR2GCKIDH2 | |
| SCHEMBL13302414 | 0.79 | POLB (0.44) | FFAR2GCKIDH2 | |
| SCHEMBL2658893 | 0.78 | GCK (0.60) | GCK | |
| SCHEMBL2655950 | 0.78 | GCK (0.66) | FFAR2GCK | |
| SCHEMBL2656181 | 0.75 | GCK (0.66) | GCK | |
| SCHEMBL3772200 | 0.74 | GCK (0.49) | GCK | |
| SCHEMBL2657285 | 0.73 | GCK (0.75) | GCK | |
| SCHEMBL184688 | 0.73 | GCK (0.69) | GCK | |
| SCHEMBL185710 | 0.73 | GCK (0.80) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104994-A2 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2008-09-04 | — | — | WO | disclosed |