Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30667998 | 1.00 | MAP3K14 (0.52) | MAP3K14 | |
| SCHEMBL26684339 | 0.93 | MAP3K14 (0.61) | MAP3K14 | |
| SCHEMBL30667886 | 0.93 | MAP3K14 (0.61) | MAP3K14 | |
| SCHEMBL26684095 | 0.90 | MAP3K14 (0.44) | MAP3K14 | |
| SCHEMBL26684440 | 0.89 | MAP3K14 (0.49) | MAP3K14 | |
| SCHEMBL26684950 | 0.87 | MAP3K14 (0.42) | MAP3K14 | |
| SCHEMBL26684554 | 0.82 | MAP3K14 (0.60) | MAP3K14 | |
| SCHEMBL30668012 | 0.82 | MAP3K14 (0.58) | MAP3K14 | |
| SCHEMBL30667857 | 0.82 | MAP3K14 (0.65) | MAP3K14 | |
| SCHEMBL26859425 | 0.82 | MAP3K14 (0.65) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217906-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |